Blistering Disorders

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Causes

Epidermolysis bullosa can be inherited both in a dominant (the patient has a 50:50 chance of getting it from a single affected parent) or recessive pattern (one affected gene needs to be present from both parents). The inherited defect causes a weakening in various parts of the skin structure, resulting in skin that is more fragile and susceptible to internal splitting and blister formation.

The closely related form, epidermolysis bullosa acquisita, displays evidence of immune dysfu...Read the full article